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Advances such as SpyTag–SpyCatcher covalent coupling (Zakeri et al., 2012), sortase-mediated ligation (Patterson et al., 2017), and aptamer- or RNA-guided cargo encapsulation (Fiedler et al., 2010) provide precise spatial, stoichiometric, and sequence-level control over how antigens or functional nucleic acids are integrated into VLP architectures
BPC-157 for gut health
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